Investigating epigenetic associations in the Canadian Longitudinal Study on Aging


The Canadian Longitudinal Study on Aging (CLSA) is a large, national, long-term study that is following approximately 50,000 individuals, who were between the ages of 45 and 85 when recruited, for at least 20 years. The CLSA aims to understand how changing biological, medical, psychological, social, lifestyle and economic aspects of people’s lives impact health and the development of disease and disability as people age.
Dr. Kobor’s Laboratory has characterized epigenetic profiles for a subset of the CLSA participants. This data will be used to determine the potential role of epigenetic modifications in maintenance of health or onset of disease, as well as to identify epigenetic-based biomarkers of health outcomes. For example, a recent study determined that epigenetic age, a marker of biological age, predicts frailty.

Members involved: Dr. Michael Kobor

Recent Publications: