Biological mechanisms associated with increased longevity in the World’s blue zones

Blue Zones are regions of the world where people on average live longer and remain healthier in old age compared to other regions. The Nicoya Peninsula of Costa Rica is one such region. The biological mechanisms leading to this increased longevity are not well understood. In collaboration with researchers from Stanford University, the Kobor Lab is investigating the association between DNA methylation, a known component of biological aging, and longevity in Blue Zone regions.